Laboratory of Dr. Binhai Zheng
Our latest paper on the impact of age / aging on axon regeneration after spinal cord injury published in Cell Report. This was a full collaboration with Dr. Wolfram Tetzlaff's lab at the International Collaboration On Repair Discoveries (ICORD), the University of British Columbia.
News stories on this paper:
The 2015 UCSD - HeadNorth Neural Injury and Regeneration Symposium was held on June 8, 2015. Local Neurosurgeon Dr. Justin Brown and ICORD Director Dr. Wolfram Tetzlaff gave talks in addition to presentations by local neural regeneration labs. See symposium website for program and pictures.
May 6-7, 2015, Wings for Life Scientific Meeting was held in Salzburg, Austria. See group photo.
which was a story on our in vivo imaging paper in Neuron (Lorenzana et al): A surviving intact branch stabilizes remaning axon architechture after injury as revealed by in vivo imaging in the mouse spinal cord.
April 21, 2015 See our Journal of Neuroscience paper on the interplay between neuron-intrinsic and extrinsic control of CNS axon repair (Geoffroy et al): Effects of PTEN and Nogo codeletion on corticospinal axon sprouting and regeneration in mice.
The 2014 UCSD - HeadNorth Neural Injury and Regeneration Symposium was held on Wednesday June 4, 2014 (1:30 - 5 pm, CNCB auditorium). Members of local neural regeneration research labs presented their research, followed by keynote address by Dr. Reggie Edgerton from UCLA. HeadNorth is a local non-profit organization that serves the need of people impacted by spinal cord injury. See meeting agenda and pictures from the meeting.
5/21/2014 Our lab was awarded a gift from the Christopher and Dana Reeve Foundation in suppport of our spinal cord research. Peter T. Wilderotter, President and CEO of the Foundation, personally presented the gift to Dr. Zheng at the Wings for Life meeting in Salzburg, Austria. Thank you, CDRF!
About the Zheng Research Group at UCSD
We are a group of scientists in the Department of Neurosciences at the University of California San Diego. Our lab uses genetically modified mice to study why axons in the central nervous system (the brain and the spinal cord) have such a limited ability to regenerate following injury. The insight gained from our research is directly relevant to the design of therapeutic interventions for spinal cord injury, white matter stroke and certain neurodegenerative disorders. In addition, we are developing ways to genetically engineer human pluripotent stem cells to study their differentiation potential and to model neurological conditions. We collaborate with other regeneration researchers on campus including Dr. Mark Tuszynski and Dr. Yishi Jin.
Science Daily story on our collaborative study with Dr. Zhigang He on PTEN in spinal axon regeneration
Science Daily story on our study of myelin inhibitors in axon growth and regeneration
To see a video produced by UCSD School of Medicine on our myelin inhibitor study, click here
To learn more about our lab, click various links above or below.